A male human with normal vision is mated with a colour blind woman. If they have children together, what is the probability that they will have a colour blind daughter?

Assignment 2B

For students with first names starting with the letters H to N.

This assignment is graded out of 110 points, and is worth 10% of your final mark. Please submit this assignment after you have completed Chapter 16 and before you write the final exam.

A.Definition/Comparison Questions

Instructions: In your own words, define the pairs of terms given below. Write in complete sentences, stating the differences and relationships between the two terms, and give specific examples where appropriate. A complete answer usually requires four to eight sentences.

Each question is worth four marks, for a total of 40 marks.

1. centriole / kinetochor

2. cleavage furrow / cell plate

3. allele / locus

4. RNA primer / DNA polymerase

5. guanine / cytosine

6. translation / anticodon

7. operator / promoter

8. conjugation / transformation

9. RFLPs / Southern blot analysis

10.pleiotropy / polygenic inheritance

B.Short Answer/Short Essay Questions

Instructions: Answer each of the questions given below in your own words. Write in complete sentences where appropriate. A complete answer usually requires one to two sentences per mark, so a three-mark question would be answered in three to six sentences. This section is worth a total of 40 marks.

(4 marks) 1. Explain how CDKs regulate cell division.

(4 marks) 2. Explain the role of transposable elements in eukaryotes.

(8 marks) 3. Using the following DNA template strand sequence, answer the questions that follow:

3’–TGCAGGAAGCTACATTAG–5’

a. What is the mRNA sequence?

b. What is the final sequence of amino acids in the peptide produced?

c. If the sequence is mutated so that adenine at position 11 is replaced with uracil, how will the peptide be affected? What kind of a mutation is this?

(5 marks)
4. a. What is an operon?

b. How do inducible operons (e.g., the lactose operon) and repressible operons (e.g., the tryptophan operon) benefit a bacterial cell?

(5 marks) 5. Explain the possible role of telomerase in cellular aging and in cancer formation.

(6 marks) 6. a. Draw a diagram to show what could happen during meiosis that would result in an egg with two X chromosomes.

b. If this egg is fertilized and develops, what are the possible karyotypes of the offspring?

(6 marks) 7. A female yellow Labrador retriever homozygous for coat colour (bbee) is mated with a male black lab. They have two chocolate puppies, three black puppies and one yellow puppy. What is the genotype of the father? Use Punnett squares to show your reasoning.

(2 marks) 8. What is a proteome, and why is it studied in addition to (or instead of) the genome?

C.Multiple Choice Questions

Instructions: Select the single best answer to each of the questions given below. Each question is worth one mark, for a total of 30 marks.

1. A zygote contains the ________ complement of chromosomes.

a. haploid

b. diploid

c. polyploid

d. spermatogenesis

e. none of these

2. How is the nucleoid of a bacterial cell replicated?

a. The linear DNA molecule is replicated from multiple origins of replication bidirectionally.

b. The linear DNA molecule is replicated from one origin of replication bidirectionally.

c. The circular DNA molecule is replicated from multiple origins of replication bidirectionally.

d. The circular DNA molecule is replicated from one origin of replication bidirectionally.

e. The circular DNA molecule is replicated from one origin of replication unidirectionally.

3. Some cats have calico coats. These result from

a. polygenic inheritance.