How does ANP affect the kidneys and what ultimate affect that that have on blood volume?
Negative Feedback Control of Blood Pressure
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Module: Foundations
Activity: Animations
Title: Negative Feedback Control of Blood Pressure
Introduction
- Explain how high or low blood pressure affects capillary blood flow.
Baroreceptors
- What is the function of baroreceptors?
The Cardiovascular Center & Organ Effect
- Explain the negative feedback loop between baroreceptors, the cardiovascular (CV) center, and the heart. Address: dropping blood pressure, heart stimulation, and hormonal vessel constriction. How do these all work together to achieve homeostasis?
Vascular Regulation
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Module: Distribution
Activity: Animations
Title: Vascular Regulation
Introduction
- a. How do Mean Arterial Blood Pressure (MABP) and Systemic Vascular Resistance (SVR) factor together to produce the total Cardiac Output (CO)?
- What systems both influence and regulate MABP and SVR thereby impacting CO?
Primary Factors That Affect Circulation
- Name the three primary factors that influence circulation.
- Blood moves from areas of high pressure toward areas of lower pressure. Describe how the right atrial and aortic pressures affect blood movement.
- Define Systemic Vascular Resistance (SVR).
- Identify and describe three factors that increase SVR.
Vasoconstriction –
Polycythemia or Dehydration –
Vessel Length –
- Cardiac Output (CO) is a product of heart rate and stroke volume. What three factors influence heart rate and stroke volume?
Structures and Functions
- Summarize how each of the following affect blood flow.
Heart –
Arterioles –
Veins & Kidneys –
- Explain ventricular importance in maintaining blood pressure.
- a. Describe ventricular activity during each of the following.
Systole –
Diastole –
- What are normal systolic and diastolic pressures for a resting adult?
c. What is the importance of blood vessel elasticity?
- If normal resting blood pressure is 120/80, then why is MABP 93?
- Explain how, and why, arterioles and small arteries affect SVR?
- How does vasoconstriction affect SVR and local blood flow?
- How does vasodilation affect SVR and local blood flow?
- Define venous return of blood.
- In what way(s) does venous return of blood affect cardiac output?
- How does increased water reabsorption by the kidneys affect blood volume and venous return?
- How does decreased water reabsorption by the kidneys affect blood volume and venous return?
- What is the body’s primary blood reservoir?
- Define venous tone.
- a. Explain the effect of venoconstriction.
b. Explain the effect of venodilation.
- Describe how venous valves and muscular movements affect venous blood flow.
- Explain how breathing contributes to venous blood flow.
Neural Regulation of Blood Pressure
- Generally describe the role of the following receptors relative to blood pressure monitoring.
- Describe each of the following neural reflexes.
Baroreceptor Reflexes –
Carotid Sinus Reflex –
Aortic Reflex –
- Describe physiological adjustments in response to dropping MABP.
Sympathetic Signals –
Parasympathetic Signals –
Heart Rate, Contractility, Venous Tone, Cardiac Output –
Vasoconstriction –
- Describe physiological adjustments in response to rising MABP.
- How do chemoreceptors in the carotid and aortic bodies contribute to re-establishing homeostasis during hypoxia, acidosis, or hypercapnia?
Hormonal Regulation of Blood Pressure
- Neural regulation of blood pressure is short-term and quick in response. What about hormonal regulation of blood pressure?
- What activates the RAA system?
- Describe the role of each of the following hormones. Name their source, too.
Renin –
Angiotensinogen –
Angiotensin I –
Angiotensin II –
- How does angiotensin II affect cells in the proximal convoluted tubules in kidney nephrons?
- a. How does angiotensin II affect target cells in the adrenal cortex?
How does this affect cardiac output?
- How does angiotensin II affect sensations of thirst? How does this contribute to blood pressure homeostasis?
- What stimulates the release of Anti-Diuretic Hormone (ADH)?
- Where is ADH produced and secreted?
- How does ADH affect smooth muscle in arteriole walls?
- How does ADH affect the kidneys? How does this contribute to blood pressure homeostasis?
- How does ADH affect sweat glands? How does this contribute to blood pressure homeostasis?
- What stimulates ANP secretion?
- How does ANP affect the kidneys and what ultimate affect that that have on blood volume?